10+ Sickle Cell Anemia Causes Genetic Pics. Sickle cells are destroyed rapidly in the bodies of people with the disease, causing anemia. It is caused by an inherited abnormal hemoglobin that decreases life expectancy.
Sickle cells can get stuck and block blood flow, causing pain and infections. The severity of symptoms varies from person to person. Signs and symptoms of sickle cell disease usually begin in early childhood.
The disorder is caused by a single base pair change in one of the genes that codes for hemoglobin, the blood protein that carries oxygen.
In part i we learned that sickle cell anemia was recognized to be the result of a genetic mutation, inherited according to the mendelian principle of incomplete dominance. It's caused by someone having two abnormal hbs genes causing the red blood cells to stiffen (take on the form of a sickle). Children and young adults can die from the disease. Sickle cell anemia is an inherited (genetic) disorder seen most commonly in people of african ancestry.
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